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Magnetic resonance perfusion or fractional flow reserve in coronary disease

New England Journal of Medicine Jun 24, 2019

Nagel E, et al. - Through an unblinded, multicenter, clinical-effectiveness trial with 918 patients who had typical angina and either two or more cardiovascular risk factors or a positive exercise treadmill test, researchers assessed whether a cardiovascular magnetic resonance imaging (MRI)–based strategy was non-inferior to a fractional flow reserve (FFR)-based strategy in terms of major adverse cardiac events. No difference in the percentage of patients who were free from angina at 12 months was observed between the two groups (cardiovascular-MRI group and FFR group). Myocardial-perfusion cardiovascular MRI was linked to a lower incidence of coronary revascularization vs FFR, along with non-inferiority to FFR with respect to major adverse cardiac events was seen amongst stable angina patients and risk factors for coronary artery disease.

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