Soltanimehr E, et al. - For the remineralization of primary teeth, researchers evaluated the effectiveness of a 980-nm diode and 10.6-μm CO₂ laser accompanied by tricalcium phosphate-5% sodium fluoride and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). Using two-way ANOVA, data were analyzed. There were significant differences in microhardness and remineralization percentage after remineralization among the material groups such that the highest mean was noted in the CPP-ACP group. No significant difference was noted after remineralization among the laser groups in microhardness or percentage of remineralization. After remineralization with CPP-ACP, the highest microhardness was achieved. The diode and CO₂ laser effectiveness were the same. There has been no synergistic impact between materials and lasers.