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Clomiphene citrate effect on testosterone level and semen parameters in 18 infertile men with low testosterone level and normal/low gonadotropines level

European Journal of Obstetrics & Gynecology and Reproductive Biology Jun 18, 2019

Surbone A, et al. - Through a retrospective study conducted on 18 infertile men with low T level and normal or low gonadotropines level, the contributors targeted to determine the effect of a 3-month course of clomiphene citrate (CC) on plasma testosterone (T) level and on semen parameters. Occurrence of 3 natural pregnancies took place during the treatment period. Hence, it was concluded that to increase plasma T level in infertile men with low T level and normal or low gonadotropines level CC was an effective and inexpensive treatment. Furthermore, increase sperm concentration even in oligospermic infertile men could be seen with the use of CC. However, no significant effect on progressive sperm motility could be seen.
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