Davis A, et al. - Researchers examined how pregnancy outcomes (biochemical pregnancy rate, clinical pregnancy rate, ongoing pregnancy rate, and ongoing pregnancy rate) in women with previous implantation failure are influenced when intravenous intralipid are administered at the time of embryo transfer. In this single-blinded randomized controlled trial of 102 women underwent analysis, 52 in the study group and 50 in control group. Two doses of 20% intravenous intralipid (Fresenius Kabi), 4 mL diluted in 250 mL normal saline was administered to women in the study arm by slow infusion. They provided the first dose immediately following oocyte recovery, and the second dose on the day of embryo transfer, 1 hour prior to the transfer. Normal saline was administered to the control group (n = 50). The intralipid vs control group had a significant difference in the biochemical pregnancy rate (40.38% vs 16%), clinical pregnancy rate (34.62% vs 14%), implantation rate (16.6% vs 6.6%), and take home baby rate [28.8% vs 10%]. Findings thereby suggest a statistically significant increase in implantation rate and live birth rate among women who receive intravenous intralipid with prior implantation failure after IVF/ICSI.