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Partial nephrectomy vs ablative therapies for cT1a renal masses: A systematic review and meta-analysis

European Journal of Surgical Oncology Jun 08, 2019

Hu X, et al. - Researchers performed this study to compare oncologic and functional outcomes after partial nephrectomy vs ablative therapies for treating clinical T1a renal masses. Searching PubMed, Embase and Cochrane Central Register, they included 20 articles incorporating 5,011 patients in this meta-analysis. Selected patients may have a significantly lower OS and higher local recurrence rates in correlation to ablation vs partial nephrectomy (PN). While the two treatments were comparable regarding CSS and DFS. On the other hand, they noted a significantly reduced risk of perioperative complication and the potential advantage of long-term renal function preservation in correlation to undergoing ablation. Ablation affords attractive treatment options for small renal masses.
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