Li H, et al. - Via performing a dose-response meta-analysis of prospective cohort studies, researchers investigated the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with the risk of depression in the older population. They identified six eligible studies representing 16,287 older adults with 1,157 cases of depression from the PubMed, Cochrane Library, Web of Science, PsycINFO, and EMBASE databases. Upon analysis, they noted a negative correlation of serum 25(OH)D concentration with the risk of depression in older adults. The risk of depression decrease by 12% in correlation with every 10-ng/mL increase in serum 25(OH)D. Finding thereby suggested a possible utility of increasing 25(OH)D levels to reduce the risk of depression in older adults.