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Determinants of the decline in mortality from acute stroke in England: linked national database study of 795,869 adults

BMJ May 27, 2019

Seminog OO, et al. - In this population based study involving 795,869 adults (aged 20 and older) who were admitted to hospital with acute stroke or died from stroke, researchers studied trends in stroke mortality rates, event rates, and case fatality, and explained the extent to which the decline in stroke mortality rates was influenced by changes in stroke event rates or case fatality. According to findings, declines in case fatality, likely driven by improvements in stroke care, contributed to the overall reduction in stroke mortality more than declines in event rates. Reduction of mortality in men and women under the age of 55 resulted solely from a decrease in fatality, whereas rates of stroke events increased in the age group from 35 to 54 years. The rise in young adults' rates of stroke events is a concern. This suggests that to reduce the occurrence of stroke in people younger than 55 years, stroke prevention needs to be strengthened.
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