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Impact of obesity and metabolic abnormalities on the risk of metachronous colorectal neoplasia after polypectomy in men

Journal of Gastroenterology and Hepatology May 26, 2019

Kim NH, et al. - Among subgroups of men according to obesity and metabolic status, researchers compared the risk of metachronous colorectal neoplasia (CRN). A total of 8,059 asymptomatic men who had ≥1 adenoma removed between 2010 and 2014 and follow-up colonoscopic surveillance until 2017 were classified into four groups according to obesity and metabolic status: metabolically healthy non-obese, metabolically-healthy obese, metabolically unhealthy non-obese, and metabolically unhealthy obese (MUO). According to findings, men with obesity as well as poor metabolic health were found to be at increased risk of metachronous advanced CRN, suggesting that after polypectomy, MUO men may need to undergo more intensive colonoscopy surveillance.

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