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Effect of a walnut diet on office and 24-hour ambulatory blood pressure in elderly individuals: Findings from the WAHA randomized trial

Hypertension Apr 20, 2019

Domènech M, et al. - Among free-living elderly people taking part in the Walnuts and Healthy Aging study (a randomized trial testing the impact of walnuts at ≈15% energy on age-related disorders), researchers assessed office blood pressure (BP) and 24-hours ambulatory BP in relation to a walnut diet vs a control diet over a period of 2 years. Of 305 participants included in a prespecified analysis, 236 (75%) completed the study (65% women; age, 69 years; 60% with mild hypertension). Participants were able to tolerate the walnuts and >98% of compliance was reported. In the walnut group and in controls, −4.61 mm Hg and −0.59 mm Hg were the respective values for adjusted changes from baseline in mean office systolic BP. Compared to controls, participants in the walnut group needed less uptitration of antihypertensive medication and overall had better regulated BP. In elderly subjects, especially in those with mild hypertension, a reduction in systolic BP was evident in relation to intake of walnuts.

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