Abaloparatide for risk reduction of nonvertebral and vertebral fractures in postmenopausal women with osteoporosis: A network meta-analysis

Osteoporosis International Apr 12, 2019

Reginster JY, et al. - In this network meta-analysis (NMA), researchers estimated the relative effectiveness of abaloparatide vs other therapies to reduce the risk of fractures in women with postmenopausal osteoporosis (PMO). In all, abaloparatide exhibited the greatest treatment effect relative to placebo in the vertebral fracture (VF) network, the nonvertebral (NVF) network, and the wrist fracture network vs other treatments. Compared with other treatments, abaloparatide had the greatest estimated possibility to prevent the fractures in the following networks: 79% for VF, 70% for NVF, and 53% for wrist fracture.

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