Safder OY, et al. - In this multicenter prospective cohort study including 511 children diagnosed with acute kidney injury (AKI), researchers assessed how the incidence of short-term mortality and morbidity in these subjects was affected by AKI severity. This study was run for two years. For diagnosing and staging AKI, the Kidney Disease Improving Global Outcomes (KDIGO) was used: stage I (mild), stage II (moderate) and stage III (severe). They found a direct relationship between the extent of AKI severity and increased mortality, length of stay (LOS) and short-term morbidity. A higher risk of mortality and longer LOS in hospital were observed in stage II and III AKI. Need for mechanical ventilation, referral to pediatric nephrology and discharge with abnormal creatinine level (above 100 uml\L) were more likely to be seen among children with stage III AKI. Factors that independently conferred risk for mortality were hypervolemia, hypocalcemia, anemia, and acidosis.