Toyama T, et al. - In a multicenter prospective cohort trial (the Gunma-CKD SPECT Study), researchers investigated if cardiovascular/cerebrovascular events could be predicted by stress myocardial perfusion single-photon emission computed tomography (SPECT) in 311 patients with chronic kidney disease (CKD) (estimated glomerular filtration rate < 60 min/mL/1.73 m²) including 50 patients on hemodialysis. Findings highlighted the possible reliability of myocardial perfusion SPECT parameters as well as of renal anemia and diabetes mellitus (DM) as prognostic markers in these patients. In patients who had end-systolic volume (ESV) < 105 mL, hemoglobin (Hb) > 12 g, and a summed stress score < 6, a higher cardiac death (CD)-free rate was found in the Kaplan-Meier analysis. Those with SDS = 0, without DM, and with Hb > 12 g, a higher major adverse cardiovascular/cerebrovascular and renal events (MACCRE)-free rate was observed.