Canivell S, et al. - In this retrospective cohort study, researchers used electronic health records from the SIDIAP database (2010-2014) to examine glycemic control after treatment in subjects with type 2 diabetes uncontrolled on ≥ 2 non-insulin antidiabetic drugs (NIADS). The study sample consisted of 15,205 patients. They noted that 48.9% of patients achieved a HbA1c < 8%, 16.2% HbA1c < 7%, and 43.1% a reduction > 1% after the first intensification. A positive relationship was observed between previous high HbA1c and the reduction of HbA1c > 1% but was inversely correlated with the attainment of HbA1c < 7% or < 8%. They reported an association of older age, male sex, higher Charlson index, and short diabetes duration with an achievement of HbA1c < 7%. Overall, findings suggested the failure of glycemic goal of HbA1c < 7% among most of the cases despite intensification.