Loeh B, et al. - Among 70 patients (48 male; mean [SD] age, 66.4 [9.0] years) with idiopathic pulmonary fibrosis (IPF), the links among physiologic measurements, survival, and quantitative high-resolution CT (HRCT) scanning indexes were examined retrospectively. Mean lung attenuation (MLA), skewness, kurtosis, peak attenuation, total lung area, inflexion point with slope, and area right of the inflexion point (AROIP) were assessed, as well as FVC, FEV₁, total lung capacity, diffusing capacity or transfer factor of the lung for carbon monoxide (Dlco), and 6-min walk distance. Correlations of HRCT scanning indexes with physiologic measurements were found. A negative correlation of MLA, peak attenuation, slope, attenuation, and AROIP with all physiologic measurements was observed. Only AROIP (among age, sex, MLA, skewness, kurtosis, FVC, and Dlco) had a marked effect on survival.