Klyne DM, et al. - Researchers compared the sensory profiles during acute low back pain (LBP) between individuals who did and did not recover by 6-months. In addition, they sought the subgroups associated with outcomes. Pain threshold (heat/cold/pressure) and conditioned pain modulation (CPM) testing were performed on individuals with acute LBP (<2 weeks of onset, N=99) after they completed questionnaires related to pain/disability, sleep, and psychological status. A comparison was done in sensory measures during the acute phase (baseline) and longitudinally (baseline/6-months) between unrecovered (≥pain and disability), partially recovered (pain and/or disability), and recovered (no pain and disability) participants at 6-months. Outcomes suggest that central sensitization is present in some but not all individuals with acute back pain. It may or may not precede poor outcome, but, may be sustained in conjunction with other psychological factors and facilitate pain persistence.