Tabata N, et al. - In this study, researchers assessed arterial stenosis and stiffness in patients with malignant diseases requiring percutaneous coronary intervention. Overall 1,003 subjects participated and were classified as having current or past malignant disease (malignant group) or no malignant disease (non-malignant group). The investigators measured ankle–brachial index (ABI) and brachial–ankle pulse wave velocity (baPWV) and assessed a composite of cardiovascular death, nonfatal myocardial infarction, stroke, and revascularization within 1 year. The malignant group exhibited markedly impaired ABI and baPWV. A cardiovascular event was detected in 148 patients. Malignancy was identified as an independent predictor of cardiovascular events in multivariate Cox hazard analysis. The malignancy group had remarkably higher follow-up baPWV values. In all, advanced and accelerated atherosclerosis was evident in patients with malignancy. Remarkably higher rates of adverse cardiovascular events were observed in these patients, and their risk might be stratified by ABI and baPWV.