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Safety of metformin in psoriasis patients with diabetes mellitus: A 17-year population-based real-world cohort study

Journal of Clinical Endocrinology and Metabolism Mar 06, 2019

Su YJ, et al. - In psoriatic patients with type 2 diabetes mellitus (T2DM), researchers studied the real-world safety of metformin using the National Health Insurance Research Database. Participants were randomized to metformin (n=5,520) or non-metformin (n=3,062) groups, according to metformin and other anti-diabetic medication prescriptions. According to findings, the metformin group and non-metformin group did not differ significantly in the risk of all-cause mortality, severe psoriasis, psoriasis-related admission, and re-admission of any-cause. Overall, the investigators suggested that metformin can be prescribed without safety concerns for diabetic psoriatic patients.

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