Vaccines help in activating the immune system and in some immunocompromised patients, this ability can be impaired, so a third dose may help in boosting the immunity response. However, there are several questions that come along with the third recommended COVID-19 dose, especially, whether it is really necessary.

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Third dose of COVID-19 vaccination for immunocompromised individuals– need of the hour

The FDA modified the emergency use authorisations (EUAs) for Pfizer and Moderna's COVID-19 vaccines to include an extra booster dosage for select immunocompromised individuals after weeks of speculation. Solid-organ transplant patients and those with diseases "thought to have a comparable degree of immunocompromise" who had previously received one of the two mRNA vaccinations are among these people. The FDA updated the Pfizer-BioNTech and Moderna messenger RNA vaccines' emergency use authorisation to allow a third dose "in certain immunocompromised individuals, specifically solid organ transplant recipients or those diagnosed with conditions that are considered to have an equivalent level of immunocompromise."