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Infants exposed to hepatitis C virus during pregnancy often are not screened for infection after delivery

American Academy of Pediatrics News May 04, 2018

Due to the opioid epidemic, the rate of hepatitis C virus infection among pregnant women increased 60% between 2006 and 2014, according to a study, yet only 30% of infants exposed to the virus were screened for infection.

The study, “Hepatitis C Virus Screening Among Children Exposed During Pregnancy,” will be published in the June 2018 issue of Pediatrics (published online May 2). Researchers analyzed a database of 87,924 pregnant women who delivered babies at Pittsburgh University Medical Center hospital and identified 1,043 (1.2 %) as having a hepatitis C virus infection.

The women infected with the virus were more likely to be younger than 30; white; have Medicaid; have opiate use disorder; and have other substance use than uninfected women. Of the 1,043 infants that delivered, 363 were receiving well-child care at the same hospital system at 1 year of age. Only 96 of the 363 infants (30%) were screened for hepatitis C virus.

Without appropriate screening, children at risk for perinatal transmission may remain undiagnosed until they become symptomatic. Hepatitis C infection can lead to irreversible liver disease. The study authors recommend consideration of a universal hepatitis C screening during pregnancy, especially in high-prevalence areas.

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