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How does bariatric surgery impact joint replacement outcomes in the morbidly obese?

Hospital for Special Surgery News Apr 05, 2017

A new study demonstrates that in morbidly obese patients, bariatric surgery performed prior to a total hip or knee replacement can reduce in–hospital and 90–day postoperative complications and improve patient health, but it does not reduce the risk of needing a revision surgery. The study was presented at the annual meeting of the American Academy of Orthopaedic Surgeons (abstract #P155).

"With our data, I think we can say with confidence that bariatric surgery prior to total joint replacement is not a harmful recommendation," said lead study author Alexander McLawhorn, MD, MBA, orthopedic surgeon at Hospital for Special Surgery in New York City. "As an orthopedic surgeon, you are not going to compromise your joint replacement outcome if you advise a morbidly obese patient to seek an opinion from a bariatric surgeon."

Morbid obesity is associated with poor postoperative outcomes after total knee arthroplasty (TKA) and total hip arthroplasty (THA), including increased risk for revision surgery, postoperative infection, and medical complications. Previous studies have shown that bariatric surgery in patients who are morbidly obese can reduce weight and comorbidities, but clinicians have not known whether the surgery is helpful or harmful to morbidly obese patients undergoing a joint replacement. Because bariatric surgery has a big impact on the metabolic system, creating a malnourished state, some clinicians have worried that the surgery might have a negative impact on total joint replacement. Others have believed it might improve outcomes, by reducing weight and thus the load on a hip or knee joint.

To shed light on the issue, researchers at Hospital for Special Surgery turned to the New York Statewide Planning and Research Cooperative System (SPARCS) database, a comprehensive all payer data reporting system. They identified all morbidly obese patients who had a THA or TKA in the state of New York between 1997 and 2011. There were 2,636 who underwent a total knee replacement and 792 who underwent a total hip replacement after bariatric surgery.

The researchers then used propensity score matching to build control groups of morbidly obese patients receiving total hips and knees without prior or subsequent bariatric surgery. Propensity score matching is a statistical technique that attempts to estimate the effect of a treatment by accounting for the covariates that predict receiving treatment. The propensity score was defined as the conditional probability of a patient undergoing bariatric surgery, given his or her baseline characteristics, including: age, year in which a total hip or total knee replacement was performed, laterality (unilateral versus bilateral surgery), sex, health care payer, region (rural versus urban), and Elixhauser comorbidities.

Statistical analyses showed that bariatric surgery lowered the comorbidity burden of patients prior to total joint replacement (P<0.0001 for TKA and P<0.005 for THA). Morbidly obese patients who had bariatric surgery had lower rates of in–hospital complications for total hip replacement (1.5% vs. 5.3%; P<0.0001) and for total knee replacement (2.7% vs. 3.9%; P=0.021). Put another way, morbidly obese patients who had bariatric surgery were 75% less likely to have in–hospital complications from a total hip replacement and 31% less likely to have in–hospital complications for a total knee replacement. The risk for 90–day postoperative complications was also lower in patients who received bariatric surgery, 14% lower in the THA group (odds ratio [OR], 0.86; P=0.041) and 61% lower in the TKA group (OR, 39%; P=0.0019). Bariatric surgery did not lower the risk of having a revision surgery or the risk for a hip dislocation.
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