Using e-cigarettes increases your odds of having a stroke, heart attack, and coronary heart disease, according to preliminary research to be presented in Honolulu, HI, at the American Stroke Association’s International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.

In 2016, 3.2% of US adults and 11.3% of high school students reported using e-cigarettes in the preceding 30 days. Its use among young people increased by 900% between 2011 and 2015.

In the largest study to date examining e-cigarettes and stroke, researchers tapped a database of 400,000 respondents. That database, the 2016 behavioral risk factor surveillance system (BRFSS) survey, collected data from residents in all 50 states about their health-related risk behaviors, chronic health conditions, and use of preventive services.

“Compared with non-users, e-cigarette users were younger [and] had a lower body mass index and a lower rate of diabetes,” said Paul M. Ndunda, MD, the study’s author and an assistant professor in the School of Medicine at the University of Kansas in Wichita, KS.

Some 66,795 respondents reported having ever regularly using e-cigarettes. The control group was the 343,856 respondents who reported having never used e-cigarettes. Odds ratios were calculated using logistic regression analysis. Researchers found compared with non-users, e-cigarette users had a:

• 71% higher risk of stroke
• 59% higher risk of heart attack or angina
• 40% higher risk of coronary heart disease
• Double the rate of cigarette smoking

They also found 4.2% of e-cigarette users reported having suffered a stroke. However, the study data did not show deaths attributable to e-cigarette use.

The American Heart Association cautions against the use of e-cigarettes, stating that e-cigarettes containing nicotine are tobacco products that should be subject to all laws that apply to these products. The Association also calls for strong new regulations to prevent access, sales, and marketing of e-cigarettes to youth and for more research into the product’s health impact.