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Brain injury in COVID-19 is revealed by magnetic resonance imaging and computed tomography

Karolinska Institutet Aug 03, 2020

Injuries in the nervous system of patients with severe COVID-19 are revealed by magnetic resonance imaging and computed tomography. In a study of 185 patients, researchers at KI and Karolinska University Hospital show an affection of microscopic blood vessels and inflammation in the brain, meninges and nerves. The results are published in Radiology.

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Many people affected by COVID-19 have few symptoms, while others become critically ill. Some suffer from changes in the smell, taste or mood and some report fatigue, this suggests an affection of the peripheral and central nervous systems. There are also reports of impaired consciousness, personality changes and memory disturbances in those most severely affected by COVID-19.  

Researchers at KI have therefore summarized findings in the brain and spinal cord in COVID-19. During the study period of March to May, 185 patients were examined at Karolinska University Hospital, all with a positive PCR-test for SARS-CoV-2. In total, 222 examinations of the brain were performed with computed tomography (CT), 47 with brain magnetic resonance imaging (MRI) and seven with spinal MRI. The study findings included stroke and brain abnormalities related to the microvasculature.

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