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Long-term outcomes of adolescent anorexia nervosa on bone

Journal of Adolescent Health Dec 17, 2018

Mumford J, et al. - Researchers examined 41 females with a history of adolescent-onset anorexia nervosa (AN) with follow-ups on bone health estimation at 5 years (T5, n = 28) or 10 years (T10, n = 13) after their first AN-related hospital admission to evaluate the persistence of the long-term impression of AN on bone health even after the normalization of body weight. They included dual-energy x-ray absorptiometry measurements of the total body, lumbar spine, and proximal femur, peripheral quantitative computed tomography at the radius and tibia, anthropometric measurements, serum biochemistry, fracture history, and a patient questionnaire for the estimation. An overall recovery of fat mass with a decline at the femoral neck and arms, lean tissue mass. A reduction in measures of radiographic bone health with no change in fracture risk was also noted representing the negative effects on bone health.
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