Association of chronic kidney disease with allopurinol use in gout treatment

JAMA Nov 09, 2018

Vargas-Santos AB, et al. - In this population-based UK cohort study, researchers evaluated if there is a relationship between allopurinol use in gout and the risk of developing stage 3 or higher chronic kidney disease. Findings suggested a link between allopurinol initiation of at least 300 mg/day with a reduced risk of renal function deterioration. Data revealed that allopurinol did not seem to be related to kidney function decline, and medical practitioners ought to consider other possible...

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General Internal Medicine Nephrology/Urology Rheumatology Clinical Pharmacology

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