Proton pump inhibitors are associated to minimal and overt hepatic encephalopathy and increase mortality in cirrhotics

Hepatology Oct 11, 2018

Nardelli S, et al. - Researchers investigated whether there was an association between minimal hepatic encephalopathy (MHE) and proton pump inhibitors (PPIs) use as well as the role of PPIs use in the development of overt HE and survival via including 310 consecutive cirrhotic patients and followed up for 14.1±12.3 months. PPIs use, previous overt HE, low albumin, low sodium and age were the variables independently related to the presence of MHE. PPIs, history of overt HE, low albumin,...
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