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Overweight and obesity may play a role in the pathogenesis of chronic spontaneous urticaria

Clinical and Experimental Dermatology Apr 20, 2018

Zbiciak-Nylec M, et al. - Experts evaluated the relationship between body parameters and the development of chronic spontaneous urticaria (CSU).They noted a probable association of CSU, especially if of long duration, with overweight and obesity, while increased body mass could result in the later onset of urticaria symptoms.

Methods

  • Authors enrolled 85 patients with CSU, who were divided into three subgroups: Patients whose only symptoms were weals, patients whose only symptom was angio-oedema, and patients with urticaria and accompanying angio-oedema.
  • They recorded the mean weight, height, body mass index (BMI), body surface area, disease duration and age of disease onset.

Results

  • Findings suggested a statistically significant association between CSU and heavier weight, higher BMI, greater affected body surface area and older age at disease onset.
  • Results demonstrated a tendency towards longer disease duration in subjects with higher BMI values.
  • Researchers did not note any statistically significant differences between the 3 subgroups.

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