• Profile
Close

Local tumor bed recurrence following partial nephrectomy in patients with small renal masses

The Journal of Urology Sep 25, 2017

Wood EL, et al. - This trial entailed the inspection of the incidence, characteristics, and management of patients who had tumor bed recurrence after partial nephrectomy. A correlation was found between local tumor bed recurrence after partial nephrectomy with several preoperative factors, with the inclusion of the presence of multiple tumors and a solitary kidney, and intra/post-operative factors such as positive surgical margin and higher pathologic stage.

Methods

  • The charts of 2,256 patients with sporadic small renal masses undergoing partial nephrectomy were appraised between 2000 and 2014.
  • The definition of local tumor bed recurrence was either: 1) detection of a new enhancing lesion specifically within the surgical defect or 2) detection of a new enhancing lesion within the same region (e.g. lower pole) as the PN site.
  • Local recurrence was noted in 44 patients (1.9%), and compared to 163 randomly selected patients who underwent PN with no recurrence for the variations in multiple characteristics.

Results

  • Patients with local tumor bed recurrence exhibited a greater tendency for solitary kidney (27% vs. 4%, p<0.01), and bilateral disease at presentation (23% vs. 10.4%, p=0.02) than the group with no recurrence.
  • There appeared to be positive margins in 15.9% of local tumor bed recurrences than 3% of the control group (p<0.01).
  • Median time between partial nephrectomy and detection of local tumor bed recurrence was reported as 23 months (range 2-107 months).
  • A correlation was outlined between the male gender, presence of a solitary kidney at the time of partial nephrectomy, positive surgical margins, presence of multiple tumors, and higher nephrometry score and pathologic staging with local tumor bed recurrence.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay