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Reconciling the effects of screening on prostate cancer mortality in the ERSPC and PLCO trials

Annals of Internal Medicine Sep 15, 2017

Gulati R, et al. - This paper contemplated if the impact of screening on prostate cancer mortality relative to no screening varied between the European Randomized Study of Screening for Prostate Cancer (ERSPC) and Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO). Taking into consideration the variations in implementation and settings, the ERSPC and PLCO yielded compatible evidence that screening caused a reduction in the prostate cancer mortality.
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