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Characterization of inflammasome-related genes in urine sediments of patients receiving intravesical BCG therapy

Urologic Oncology: Seminars and Original Investigations Sep 14, 2017

Poli G, et al. - This study aspired to estimate whether nucleotide oligomerization domain-like receptors (NLRs) show alterations during Bacillus Calmette-Guérin (BCG) instillations. The importance of NLRP4 and NLRP9 in urothelial carcinoma had been outlined. Playing a relevant role in decision making for early radical surgery, the assessment of NLRP4 and NLRP9 expression levels could help to predict the BCG failure.
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