• Profile
Close

Occupation and risk of developing rheumatoid arthritis: Results from a population-based case-control study

Arthritis Care & Research Aug 14, 2017

Ilar A, et al. – In this population–based study, the physicians examined the association between occupation and the risk of anti–citrullinated protein antibody (ACPA) + rheumatoid arthritis (RA) or ACPA– RA. They illustrated that particularly occupations related to potential noxious airborne agents were associated with an increased risk of ACPA+ or ACPA– RA.

Methods

  • This study enrolled 3,522 cases and 5,580 controls from the Swedish population–based EIRA case–control study.
  • To accumulate information on work history and lifestyle factors, a questionnaire was used.
  • For serologic analyse, blood samples were collected.
  • To calculate the odds ratio (OR) of RA associated with the last occupation before study inclusion, unconditional logistic regression was used.
  • Analyses were conducted with adjustments for known environmental exposures and lifestyle factors, including pack years of cigarette smoking, alcohol use, body mass index (BMI) and education.

Results

  • Investigations revealed that among men, bricklayers and concrete workers (OR: 2.9, 95% CI: 1.4–5.7), material handling operators (OR: 2.4, 95% CI: 1.3–4.4) and electrical and electronics workers (OR: 2.1, 95% CI: 1.1–3.8), had an increased risk of ACPA+ RA.
  • For ACPA– RA, bricklayers and concrete workers (OR: 2.4, 95% CI: 1.0–5.7) and electrical and electronics workers (OR: 2.6, 95% CI: 1.3–5.0) had an increased risk.
  • Among women, assistant nurses and attendants had a moderately increased risk of ACPA+ RA (OR: 1.3, 95% CI: 1.1–1.6).
  • No occupations were significantly associated to ACPA– RA among women.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay