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Factors affecting central corneal thickness measurement agreement between Scheimpflug imaging and ultrasound pachymetry in keratoconus

British Journal of Ophthalmology Sep 28, 2020

Sorkin N, Ohri A, Jung H, et al. - In this post hoc analysis within a prospective, observational non-randomised study, researchers sought to assess the agreement of central corneal thickness (CCT) measurement between Scheimpflug imaging and ultrasound (U/S) pachymetry in keratoconic eyes, and examine factors that affect the agreement. This investigation was carried out at the Kensington Eye Institute, Toronto, Ontario, Canada, included crosslinking candidates with progressive keratoconus (KC). In total, 794 keratoconic eyes of 456 patients with a mean age of 27.6 ± 8.0 years (69.7% males and 49.6% right eyes) were involved. The agreement between Scheimpflug imaging and U/S pachymetry in KC for CCT measurement was moderate. Scheimpflug and U/S CCT measurements should not be used interchangeably to ensure the safety of crosslinking in keratoconic corneas, particularly in steep corneas and corneas with decentred cones. Scheimpflug and U / S CCT measurements should not be used interchangeably to ensure the safety of crosslinking in keratoconic corneas, particularly in steep corneas and corneas with decent cones.

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