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Relationship between hemoglobin and insulin-like growth factor-1 in children and adolescents with idiopathic short stature

BMC Endocrine Disorders Aug 09, 2020

Zhao Q, Zhang M, Ji B, et al. - In this cross-sectional analysis, researchers intended to determine if there is an association between insulin-like growth factor-1 (IGF-1) and hemoglobin (Hb) in children with idiopathic short stature (ISS). The sample consisted of 178 children and adolescents with ISS who were recruited from March 2013 to February 2019. Data reported that the mean levels of IGF-1 standard deviation scores (SDS) and Hb were − 0.99 (− 1.60 - -0.09) and 131.81 ± 9.36 g/L, respectively. The data presented in this work showed a connection between Hb and IGF-1 in Chinese children and adolescents with ISS. IGF-1 levels increased with Hb elevation, but when Hb concentration reached a certain amount, with Hb increasing, IGF-1 then decreased.

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