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Left ventricular systolic function in patients with systemic lupus erythematosus and its association with cardiovascular events

Journal of the American Society of Echocardiography Jul 04, 2020

Gegenava T, Gegenava M, Beekman GMS, et al. - The present study was undertaken to investigate left ventricular (LV) systolic function in a large cohort of patients with systemic lupus erythematosus (SLE) applying standard echocardiographic assessments and global longitudinal strain (GLS) by two-dimensional speckle-tracking analysis. They further tested the correlation between echocardiographic parameters and the occurrence of cardiovascular. Researchers examined a sum of 102 patients with SLE (88% women; mean age, 43 ± 14 years) undergoing a dedicated multidisciplinary assessment. The data revealed that LV systolic function as assessed by LV GLS is significantly impaired and associated with cardiovascular events in patients with SLE, potentially representing a new tool to improve risk stratification in these patients.

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