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Monitoring occurrence of liver-related events and survival by transient elastography in patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease

Clinical Gastroenterology and Hepatology Jul 04, 2020

Petta S, Sebastiani G, Viganò M, et al. - Researchers examined whether patients at risk for liver-related and extrahepatic events could be identified in a large cohort of patients with nonalcoholic fatty liver disease (NAFLD) and compensated advanced chronic liver disease by using baseline liver stiffness measurements (LSMs) and their changes. In this retrospective analysis of 1,039 consecutive patients with NAFLD with a histologic diagnosis of F3–F4 fibrosis and/or LSMs > 10 KPa, follow up was performed for at least 6 months; LSMs were assessed using FibroScan using the M or XL probe and were recorded at baseline and within 1 year from the last follow-up examination. Per findings, baseline LSM and change in LSM are linked with risk of liver-related events and mortality among patients with NAFLD and compensated advanced chronic liver disease.

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