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Epidemiology and risk factors of infective endocarditis in a tertiary hospital in China from 2007 to 2016

BMC Infectious Diseases Jul 01, 2020

Wu Z, Chen Y, Xiao T, et al. - In this study, the trends in epidemiology and the risk factors related to the prognosis of infective endocarditis were explored in a tertiary hospital over the past ten years. Researchers conducted a retrospective cohort study including a total of 407 consecutive patients who were admitted with infective endocarditis. They examined clinical characteristics and the risk factors related to the prognosis of infective endocarditis during this period. They enrolled a sum of 407 patients with infective endocarditis, the average age was 48 ± 16 years old with an increasing trend and in-hospital mortality rate was 10.6% and the one-year mortality rate was 11.3%. No significant changes were found in the overall incidence of infective endocarditis, but the clinical features of infective endocarditis had slightly changed during the past ten years. It was demonstrated that Streptococci infective endocarditis was still predominant. It was shown that patients with hemodialysis, pulmonary hypertension, Pitt scores ≥ 4, and vegetation length > 30 mm had a worse in-hospital outcome.

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