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Holmium laser enucleation of the prostate for very large benign prostatic hyperplasia (≥ 200 cc)

World Journal of Urology Mar 27, 2020

Zell MA, Abdul-Muhsin H, Navaratnam A, et al. - This study explored the effectiveness and risks correlated with performing holmium laser enucleation of the prostate (HoLEP) on glands ≥ 200 cc. A prospective maintained database was applied to include all consecutive benign prostatic hyperplasia (BPH) patients with gland size ≥ 200 cc who had undergone HoLEP. Researchers recruited a total of 88 individuals in the study. Patient preoperative, intraoperative, postoperative outcomes and complications were reported. Gland sizes 200–299 cc and ≥ 300 cc stratified subgroup analysis of outcomes. Using Kruskal–Wallis and Fisher exact test, univariate analysis was conducted to compare the two groups. There were 88 patients with a mean preoperative gland size of 255.9 cc (200–770 cc). Holmium laser enucleation for prostate glands volume > 200 cc was found to be a feasible with minimal morbidity. For BPH, the evidence further reinforce the size independence success of this method.

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