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The prognostic value of routine preoperative blood parameters in muscle- invasive bladder cancer

BMC Urology Mar 26, 2020

Zhang J, Zhou, X Ding H, et al. - In this study, the prognostic value of routine preoperative blood parameters in muscle-invasive bladder cancer (MIBC) following radical cystectomy (RC) was explored. Researchers retrospectively obtained data of 202 individuals with MIBC who had undergone RC at the institution between October 2007 and August 2018. They applied the median preoperative neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and hemoglobin (HGB) values as cutoffs to form the low and high NLR, low and high PLR, and low and high HGB groups, respectively. Via using chi-square and t tests, the clinicopathologic characteristics of each group were compared. They further utilized Kaplan-Meier survival and multivariate Cox regression analyses to analyze prognosis. For the prognosis of MIBC individuals, preoperative peripheral blood HGB was found to be an independent risk factor. The outcomes highlighted that HGB may be a beneficial prognostic marker for MIBC individuals undergoing RC.

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