Urinary tract infections and risk of squamous cell carcinoma bladder cancer: A Danish nationwide case-control study

International Journal of Cancer Dec 26, 2019

Pottegård A, et al. - In this Danish nationwide case-control study including histologically confirmed bladder cancer cases (2000-2015; n = 12,271) and age- and gender-matched cancer-free controls, researchers examined the link between urinary tract infections (UTIs), indicated by use of specific antibiotics, and risk of squamous cell carcinomas (SCC) of the bladder. They found 333 SCC cases (2.7% of all bladder cancers). They found the link of high-use (≥ 10 prescriptions) of UTI-specific antibiotics, vs no use (0-1 prescriptions), with SCC with an OR of 11.4 and a definite dose-response pattern. Following adjustment for use of UTI-specific antibiotics, they found no link between phenoxymethylpenicillin (an antibiotic not used against UTIs) use and SCC. They also identified no association between UTI-specific antibiotic use and urothelial carcinomas. Overall, findings revealed a strong, dose-dependent, as well as a specific link of common UTIs with the risk of SCC of the bladder.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free.
  • 55 lakhs+ doctors trust M3 globally

  • Nonloggedininfinity icon
    Unlimited access to original articles by experts
  • Nonloggedinlock icon
    Secure: we never sell your data
  • Signing up takes less than 2 mins
Try M3 India / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay