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Estimating the prevalence of congenital heart disease among adolescents and adults in Colorado adjusted for incomplete case ascertainment

American Heart Journal Dec 13, 2019

Duca LM, Pyle L, Khanna AD, et al. - Researchers used log-linear capture-recapture methods to estimate the prevalence of congenital heart defects (CHDs) in adolescents and adults living in Colorado during 2011–2013, accounting for incomplete case ascertainment. They found 12,293 unique people having CHDs (2,481 adolescents and 9,812 adults) in one or more primary data sources. Among adolescents and adults in Colorado, the crude prevalence of CHDs was estimated to be 3.22 per 1,000 people (95% CI 3.19–3.53). An estimated total adolescent and adult CHD population of 23,194 and adjusted prevalence of 6.07 per 1,000 people were yielded by the ultimate capture-recapture model, after accounting for incomplete case ascertainment. This suggested the non-identification of 47% of the cases in the catchment area in the case-identifying data sources. The necessity for additional specialized care facilities for this population with CHDs was emphasized by the observed high prevalence rates.
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