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Prenatal alcohol exposure affects renal function in overweight schoolchildren: Birth cohort analysis

Pediatric Nephrology Dec 12, 2019

Correia-Costa L, Schaefer F, Afonso AC, et al. - By performing this prospective longitudinal study, researchers focused on the potential link of maternal alcohol intake during pregnancy with the offspring renal function, taking into account potential confounding by intrauterine growth and children’s current nutritional status. They analyzed a random sample including 1,093 children from a population-based birth cohort. At 7 years of age, the evaluation of anthropometrics and estimated glomerular filtration rate (eGFR) was done. Findings revealed that at 7 years of age, children with prenatal alcohol exposure had significantly lower eGFR. In this study, a dose-dependent adverse influence of prenatal alcohol exposure on renal function at school age was observed in overweight and obese children.
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