• Profile
Close

FGF8, FGF10 and FGF receptor 2 in foreskin of children with hypospadias: An analysis of immunohistochemical expression patterns and gene transcription

Journal of Pediatric Urology Nov 19, 2019

Haid B, Pechriggl E, Nägele F, et al. - Skin samples from the ventrolateral aspect of the foreskin of 32 individuals with hypospadias (17 distal and 15 proximal) and ten normal foreskin samples were investigated by immunohistochemistry in order to examine expression patterns and transcription levels of FGF8, FGF10, and FGF Receptor 2 (FGFR2) in individuals with hypospadias vs normal controls. In comparisons of normal foreskin to the foreskin of individuals with hypospadias, notable variations in localization and distribution of FGF8, FGF10, and FGFR2 were noted, whilst no variation in the quantitative expression of these markers on the mRNA level was seen. This validated the notion that during the embryogenesis of hypospadias, penile skin is impacted by the embryological aberrations as well.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay