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Processed meat intake and bladder cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) cohort

Cancer Epidemiology, Biomarkers & Prevention Oct 30, 2019

Xu X - Since the results concerning the relationship between processed meat intake and bladder cancer risk in several observational investigations have been inconsistent, this researcher examined the link between processed meat consumption and bladder cancer risk in a cohort comprising 101,721 individuals in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Participants were observed over a median duration of 12.5 years. After this time frame, overall 776 new cases of bladder cancer were documented. After multivariate adjustment, findings revealed a higher risk of bladder cancer in correlation with the consumption of processed red meat. This large prospective analysis generated findings that bladder cancer risk rises with the cumulative consumption of processed red meat. After multivariable adjustment, there was only a suggestive, but not significant, association between intake of total processed meat and bladder cancer.

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