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Predictive factors for response to salvage stereotactic body radiotherapy in oligorecurrent prostate cancer limited to lymph nodes: A single institution experience

BMC Urology Sep 17, 2019

Oehler C, Zimmermann M, Adam L, et al. - Researchers investigated if stereotactic body radiotherapy (SBRT) results among patients presenting with limited nodal recurrence following radical prostatectomy (RP) improve with a better case selection. They performed a single-institution retrospective analysis of patients who exhibited 1–3 lymph node (LN) recurrences (N1 or M1a) on 18F-Choline PET/CT. Prior therapy included RP ± salvage radiotherapy (RT), in absence of any systemic therapy. They retrospectively analyzed 25 patients treated with SBRT. Outcomes suggest that SBRT for PCa patients with 1–3 LN recurrence after RP (± salvage RT) might lead to better biochemical control when delivered to larger sized (≥ 14 mm) LN metastases. This study is hypothesis generating and results should be tested in a larger prospective trial.
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