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Correlation of triglyceride to high-density lipoprotein cholesterol ratio with nonalcoholic fatty liver disease among the non-obese Chinese population with normal blood lipid levels: A retrospective cohort research

Lipids in Health and Disease Aug 14, 2019

Chen Z, et al. - Through a retrospective cohort study involving 9,838 non-obese Chinese individuals without dyslipidemia who were free of nonalcoholic fatty liver disease (NAFLD), researchers examined the relationship of triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio with NAFLD. The cumulative incidence of NAFLD in non-obesity people was 8.69% among the overall population, during a median follow-up period of 2.9 years; its incidence was steadily improved across the quartiles of TG/HDL-C ratio. In higher quartiles, the HR of NAFLD was 2.10, 3.11, and 3.40, respectively. Additionally, the area under the receiver operator characteristic curve of TG/HDL-C ratio was 0.70 and 0.72 in males and females, respectively. The final values were dramatically greater than the other lipid index. Hence, an independent association between TG/HDL-C and NAFLD in the non-obese Chinese population without dyslipidemia was concluded; moreover, TG/HDL-C could be used as a better predictor for NAFLD.

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