• Profile
Close

Current management and predictive factors of lymph node metastasis of appendix neuroendocrine tumors: A national study from the French Group of Endocrine Tumors (GTE)

Annals of Surgery Jun 17, 2019

Rault-Petit B, et al. - In this largest study using the latest pathological criteria for completion right hemicolectomy (RHC) in appendix neuroendocrine tumor (A-NET), researchers sought to determine the predictive factors of lymph node involvement (LN+) in patients with A-NET. Among 403 patients, A-NETs were: within tip (67%), body (24%) or base (9%) of the appendix; tumor size was < 1 cm (62%), 1 to 2 cm (30%), or >2 cm (8%); grade 1 (91%); mesoappendix involvement 3 mm (5%); lymphovascular (15%) or perineural (24%) invasion; and positive resection margin (8%). According to the European NeuroEndocrine Tumor Society (ENETS) recommendations, RHC was recommended in 85 patients (21%). The ENETS guidelines agreed to the multidisciplinary tumor board for complementary RHC in 89%. Lymph node (LN) resection was done in 100 (25%) patients undergoing RHC; 26 of these had LN+. They noted tumor size (best cut-off at 1.95 cm), lymphovascular and perineural invasion, and pT classifications to be correlated with LN+. LN+ was noted in 8 (18%) patients among the 44 patients who underwent RHC for a tumor of 1 to 2 cm in size. This subgroup of patients was identified to have no predictive factor of LN+ (base, resection margins, grade, mesoappendix, lymphovascular, perineural involvement).
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay