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Impact of delayed radioiodine therapy in intermediate/high-risk papillary thyroid carcinoma

Clinical Endocrinology May 24, 2019

Kim M, et al. - Researchers assessed if the time interval between total thyroidectomy and radioactive iodine therapy (RAIT) impacts clinical outcomes in intermediate-to-high-risk papillary thyroid carcinoma (PTC). The study sample consisted of 720 PTC patients who received RAIT for <90 or 90–180 days (early and delayed groups, n=360 each) after thyroidectomy. According to this retrospective propensity score-matched cohort study, delayed RAIT was not significantly linked to worse disease-free survival or overall survival. Overall, the authors concluded that delaying the first RAIT in intermediate-to-high-risk PTC until 180 days following total thyroidectomy had no impact on re-staging, recurrence and death.

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