4 new non-BRCA genes identified with increased risk of Breast Cancer

M3 Global Newsdesk Oct 05, 2018


“Since the discovery of BRCA1 and BRCA2,multiple high- and moderate-penetrance genes have been reported as risk factors for hereditary breast cancer, ovarian cancer, or both; however, it is unclear whether these findings represent the complete genetic landscape of these cancers,” wrote researchers, led by Hsiao-Mei Lu, PhD, Ambry Genetics, Aliso Viejo, California.

At least 3% of cancer cases are due to hereditary variation in cancer predisposition genes,...

Obstetrics & Gynaecology Oncology Research

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